Sources: Chemical Compounds

Antimicrobial compounds from natural sources

Infectious diseases are one of the main causes of morbidity and mortality worldwide. Nowadays many infections are often caused by multi-resistant microorganisms resulting in difficult to treat diseases and, consequently, substantial increases in healthcare costs. The relative easy access to the antimicrobials and also the massive employment of these compounds for industrial purposes, including ...

Chemical Compounds as Carcinogenic Agents

A review of the progress made in the study of the carcinogenic properties of chemical compounds, incorporating literature published during the triennial period between the First and Second International Cancer Congresses, was presented to the Second International Congress in Brussels, in September 1936, and was subsequently reprinted with an addendum covering most of the literature published up...

Developing antimicrobial compounds from natural sources

Predicting Biological Functions of Compounds Based on Chemical-Chemical Interactions

Given a compound, how can we effectively predict its biological function? It is a fundamentally important problem because the information thus obtained may benefit the understanding of many basic biological processes and provide useful clues for drug design. In this study, based on the information of chemical-chemical interactions, a novel method was developed that can be used to identify which...

Chemical Simulation and Quantum Chemical Calculation of Lignin Model Compounds

The conformational preferences of the lignin guaiacyl structural unit were studied by several quantitative chemistry calculation methods using vanillin as a model compound. The potential energy surfaces of the vanillin molecule were scanned by the methods of HF and DFT to find the most stable conformation, as well as three local minimum conformations and six transient conformations. Bonds stren...